Body Conditioning Scoring in Rodents


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Body Conditioning Scoring for Rodents

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In Vivo Models Inflammation Xenograft Studies PK / TOX Rapid-turnaround

Body Conditioning Scoring: A rapid and accurate method for assessing health status in laboratory rodents.

Washington Biotechnology, Inc. now includes Body Conditioning Scoring ,without additional charge, on all of our rodent studies extending a week or more.

This scoring is in addition to our standard observations regarding toxicity observations, if any, on our studies. And this does not replace reported toxicity effects in TOX studies.

Washington Biotechnology, Inc. includes this service to provide a useful evaluation of animal health status and to provide you with quality information throughout your study.

BODY CONDITIONING (BC) SCORING METHOD:

BC1             Animal emaciated:
-          skeletal structure extremely prominent
-          vertebrae distinctly segmented

BC2             Animal underconditioned:
-          segmentation of vertebral column evident
-          dorsal pelvic bones are readily palpable

BC3             Animal well-conditioned:
-          vertebrae and dorsal pelvis not prominent
-          both palpable with slight pressure

BC4             Animal overconditioned:
-          spine is a continuous column
-          vertebrae palpable only with firm pressure

BC5             Animal obese:
-          animal is smooth and bulky
-          bone structure disappear under flesh and subcutaneous fat

REFERENCES:

M. Ullman-Cullere and C. Foltz.

"Body Conditioning Scoring: A Rapid and Accurate Method for Assessing Health Status in Mice"
Laboratory Animal Science, 49, No. 3, 1999.

M. E. Easterly, C.J. Foltz and M.J. Paulus.

"Body Conditioning Scoring: Comparing Newly Trained Scorers and Micro-Computed Tomography Imaging"
Lab Animal, 30, No. 3, 2001.