Obesity Models


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WASHINGTON BIOTECHNOLOGY, INC.

Now in our 24th Year of Service in Drug Development

Obesity Models

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Obesity Models

Our services for efficacy studies in treatments of obesity include in vivo models with ob/ob or diet-induced obese (DIO) mice. We can provide a custom protocol for your investigation or use client protocol.

Efficacy Studies in ob/ob Mice ---

Ob/ob mice

Obesity diet

Body weights

Glucose levels (fed/fasted)

Insulin determinations (plasma)

Glucose tolerance testing (GTT)

Organ collections and preservation (snap-frozen): liver, kidney, skeletal muscle (leg), adipose tissue

Urine collections

PK sampling

Efficacy Studies in DIO Mice ---

DIO C57BL/6 mice 18-22 weeks on High Fat Diet (HFD)

Age-matched lean mice

Body weights

Glucose levels (fed/fasted)

Insulin determinations (plasma)

Glucose tolerance testing (GTT)

Organ collections

PK sampling

Controls: age-matched lean mice

Reference: Rosiglitazone

Please contact us for further information and a custom quotation.

Your Resource for In Vivo Accuracy