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Inflammation Models
We are continually expanding our line of In Vivo Inflammation Models. Recent additions include:
EAE/ Peptide Mouse Models for Multiple Sclerosis
Washington Biotechnology has validated two models:
Washington Biotechnology, Inc. has validated in SJL mice an EAE model that demonstrates relapsing-remitting disease episodes over a 30 day period, using Dexamethasone as positive prophylactic and therapeutic control. Our PLP- induced EAE Model features clearly defined disease parameters and scoring in reliable protocols for the prophylactic or therapeutic efficacy testing.
Washington Biotechnology, Inc. has validated in C57BL/6 mice an EAE model that shows a progressive chronic disease phenotype using Dexamethasone as positive prophylactic or therapeutic control. Our model provides clearly defined efficacy for both prophylactic and therapeutic treatments with Dexamethasone.
The WBI MOG – EAE Model incorporates careful attention to study procedures, reagent quality and clear definition of disease parameters and scoring to provide reliable and cost-effective studies for assessment of compound efficacy.
PG-PS 10S Rat Model
In the PG-PS 10S Rat Model an initial acute inflammatory response is seen within 3-6 days post-injection followed by a decline. A chronic response follows with a peak in measurements at approximately 12-16 days post-PG-PS 10S. It is a valuable model for assessment of the efficacy of therapeutic and prophylactic compounds on the acute and chronic inflammatory responses, especially for arthritis studies.
Body Conditioning Scoring for Rodents
This service is now included without additional charge on all of our rodent studies extending a week or more.
This scoring is in addition to our standard observations regarding toxicity observations, if any, on our studies. And this does not replace reported toxicity effects in TOX studies.
We include this service to provide a useful evaluation of animal health status and to provide you with quality information throughout your study.
Scientific Meetings
Washington Biotechnology regularly exhibits at major international scientific meetings.
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American Association for Cancer Research (AACR) 100th Annual Meeting
Denver, CO April 18-22, 2009 Exhibit Booth 1369 |
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Inflammation Research Association |
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American Society for Cell Biology |
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American Society of Human Genetics |
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Biotechnica, Hannover, Germany |
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ENDO |
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Neuroscience |
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Experimental Biology |
Institutional Vendor Product Shows
USA - including UC San Diego, UCSF, UC Berkeley, UC Santa Cruz, Stanford University, Lawrence Livermore National Laboratory, Rocky Mountain National Laboratory, TSRI, University of Texas Medical Center, University of Chicago, University of Illinois, Duke University Medical Center, Resarch Triangle Park (RTP), University of Michigan, University of Washington, University of Pennsylvania, University of Nevada, Washington University St. Louis. VA Palo Alto (VAPA), Walter Reed Army Research Institute (WAIR) and Children's Hospital of Oakland Research Institute (CHORI).
Canada - including University of Alberta, University of Calgary, University of British Columbia, University of Western Ontario and University of Toronto.
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