Pristane-Induced Arthritis Model

 

Pristane-Induced Arthritis (PIA)

A model that most closely simulates the autoimmune RA condition in humans
Species Rat
Groups
  • Vehicle
  • Positive Control (Dexamethasone)
  • One group for each dose of each test compound
Test Duration 30 days
Readouts Arthritic Index, body weights
Optional

Paw volumes, histopathology, cytokines, and collagen titers